AKT pan inhibitor
Showing 1 - 25 of 8,258
Bile Acids in Acute Insulin Resistance
Recruiting
- PI3K Gene Mutation
- +4 more
- Drug-induced acute insulin resistance due to PI3K inhibitor, AKT inhibitor, or mTOR inhibitor
-
New York, New YorkColumbia University Medical Center
Oct 6, 2022
Advanced Malignant Solid Tumor, Stage III Cutaneous Melanoma AJCC v7, Stage III Prostate Cancer AJCC v7 Trial in New Brunswick
Active, not recruiting
- Advanced Malignant Solid Neoplasm
- +9 more
- Akt Inhibitor MK2206
- Hydroxychloroquine
-
New Brunswick, New JerseyRutgers Cancer Institute of New Jersey
Jan 25, 2023
PARP Inhibitor for Esophageal Squamous Cell Carcinoma Trial (Fluzoparib monotherapy or Fluzoparib with Camrelizumab(Only
Not yet recruiting
- PARP Inhibitor for Esophageal Squamous Cell Carcinoma
- Fluzoparib monotherapy or Fluzoparib with Camrelizumab(Only non-small cell lung cancer arm) ,or Fluzoparib combined with capecitabine (only rectal cancer arm))
- (no location specified)
Sep 24, 2023
CNS Lymphoma, Gastric Mantle Cell Lymphoma, Recurrent Mantle Cell Lymphoma Trial in Houston (Akt/ERK Inhibitor ONC201,
Terminated
- Central Nervous System Lymphoma
- +6 more
- Akt/ERK Inhibitor ONC201
- +2 more
-
Houston, TexasM D Anderson Cancer Center
Mar 30, 2022
Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma Trial in Canada (Laboratory Biomarker Analysis, Pharmacological
Completed
- Recurrent Plasma Cell Myeloma
- Refractory Plasma Cell Myeloma
- Laboratory Biomarker Analysis
- +3 more
-
Calgary, Alberta, Canada
- +4 more
Feb 10, 2022
Advanced Solid Tumor Trial in Guangzhou (YL-17231)
Recruiting
- Advanced Solid Tumor
-
Guangzhou, Guangdong, ChinaSun Yat-sen University Cancer Center
Oct 5, 2023
Premenopausal Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer Trial in Taipei City (Goserelin, Fulvestrant,
Recruiting
- Premenopausal Breast Cancer
- +2 more
- Goserelin
- +3 more
-
Taipei City, TaiwanDepartment of Oncology, National Taiwan University Hospital
Feb 7, 2023
Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma Trial in United States
Completed
- Endometrial Adenocarcinoma
- +4 more
- Akt Inhibitor MK2206
- Laboratory Biomarker Analysis
-
Boston, Massachusetts
- +6 more
Jan 13, 2022
Esophageal Cancer Trial in Hat yai (BKM120)
Terminated
- Esophageal Cancer
-
Hat yai, Songkhla, ThailandSongklanagarind Hospital, Prince of Songkla University
Oct 3, 2021
Colorectal Adenomatous Polyp, Colorectal Carcinoma, Familial Adenomatous Polyposis Trial in United States (procedure, drug,
Not yet recruiting
- Colorectal Adenomatous Polyp
- +3 more
- Biopsy
- +5 more
-
Ann Arbor, Michigan
- +4 more
Jan 3, 2023
Breast Cancer Trial in Boston (Ipatasertib, Fulvestrant, Aromatase Inhibitor)
Recruiting
- Breast Cancer
- Ipatasertib
- +3 more
-
Boston, MassachusettsMassachusetts General Hospital Cancer Center
Oct 25, 2021
Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma, Recurrent Adenoid Cystic Carcinoma Trial in Boston (CB-103,
Not yet recruiting
- Adenoid Cystic Carcinoma
- +2 more
- CB-103
- +2 more
-
Boston, MassachusettsDana Farber Cancer Institute
Mar 14, 2023
Triple Negative Breast Cancer Trial in Madison (Akt/ERK Inhibitor ONC201, Methionine-Restricted Diet)
Terminated
- Triple Negative Breast Cancer
- Akt/ERK Inhibitor ONC201
- Methionine-Restricted Diet
-
Madison, WisconsinUniversity of Wisconsin Carbone Cancer Center
Feb 11, 2022
Breast Tumor, Breast Cancer, Hormone Receptor Positive Tumor Trial in Shanghai (PIK3CA inhibitor, AKT inhibitor, Carrelizumab)
Recruiting
- Breast Neoplasm
- +4 more
- PIK3CA inhibitor
- +12 more
-
Shanghai, Shanghai, ChinaBreast cancer institute of Fudan University Cancer Hospital
Jan 2, 2023
Uveitis Trial in United States (Izokibep, Prednisone/Prednisolone)
Active, not recruiting
- Uveitis
-
Los Angeles, California
- +3 more
Jul 18, 2022
Estrogen Receptor Positive Breast Cancer Trial in United Kingdom (AZD5363, Placebo, Fulvestrant)
Active, not recruiting
- Estrogen Receptor Positive Breast Cancer
- AZD5363
- +2 more
-
Manchester, Greater Manchester, United Kingdom
- +20 more
Aug 5, 2022
Seborrheic Keratosis Trial in Santa Tecla (SM-020)
Recruiting
- Seborrheic Keratosis
-
Santa Tecla, La Libertad, El SalvadorZepeda Dermatologia
Aug 20, 2022
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Metastatic
Not yet recruiting
- FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
- +4 more
- Computed Tomography
- +3 more
- (no location specified)
Sep 13, 2022
Advanced Solid Tumors Harboring MAPK Pathway Alterations Trial in Shandong (QLH11906)
Recruiting
- Advanced Solid Tumors Harboring MAPK Pathway Alterations
-
Shandong, ChinaShandong Cancer Hospital
Aug 3, 2022
Recurrent Langerhans Cell Histiocytosis, Refractory Langerhans Cell Histiocytosis Trial (Biopsy, Biospecimen Collection,
Not yet recruiting
- Recurrent Langerhans Cell Histiocytosis
- Refractory Langerhans Cell Histiocytosis
- Biopsy
- +3 more
- (no location specified)
Dec 22, 2022
Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma Trial in Houston (AL101, Therapeutic Conventional Surgery)
Recruiting
- Adenoid Cystic Carcinoma
- Metastatic Adenoid Cystic Carcinoma
- AL101
- Therapeutic Conventional Surgery
-
Houston, TexasM D Anderson Cancer Center
Jun 29, 2022
Metastatic Breast Cancer Trial in Spain (Ipatasertib, Trastuzumab, Pertuzumab)
Recruiting
- Metastatic Breast Cancer
- Ipatasertib
- +2 more
-
Badalona, Barcelona, Spain
- +9 more
Oct 24, 2022